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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
J. Virol. 2008 82: 5117. [Full Text] [PDF] FREE  

Virus-Cell Interactions:

Sundaram A. Vishwanathan and Eric Hunter

Importance of the Membrane-Perturbing Properties of the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 to Viral Fusion
J. Virol. 2008 82: 5118-5126. [Abstract] [Full Text] [PDF]  

Filippo Pacciarini, Silvia Ghezzi, Filippo Canducci, Amy Sims, Michela Sampaolo, Elena Ferioli, Massimo Clementi, Guido Poli, Pier Giulio Conaldi, Ralph Baric, and Elisa Vicenzi

Persistent Replication of Severe Acute Respiratory Syndrome Coronavirus in Human Tubular Kidney Cells Selects for Adaptive Mutations in the Membrane Protein
J. Virol. 2008 82: 5137-5144. [Abstract] [Full Text] [PDF]  

Timothy R. Wagenaar, Suany Ojeda, and Bernard Moss

Vaccinia Virus A56/K2 Fusion Regulatory Protein Interacts with the A16 and G9 Subunits of the Entry Fusion Complex
J. Virol. 2008 82: 5153-5160. [Abstract] [Full Text] [PDF]  

Livia Donaire, Daniel Barajas, Belén Martínez-García, Llucia Martínez-Priego, Israel Pagán, and César Llave

Structural and Genetic Requirements for the Biogenesis of Tobacco Rattle Virus-Derived Small Interfering RNAs
J. Virol. 2008 82: 5167-5177. [Abstract] [Full Text] [PDF]  

Guruprasad R. Medigeshi, Alec J. Hirsch, Daniel N. Streblow, Janko Nikolich-Zugich, and Jay A. Nelson

West Nile Virus Entry Requires Cholesterol-Rich Membrane Microdomains and Is Independent of vβ3 Integrin
J. Virol. 2008 82: 5212-5219. [Abstract] [Full Text] [PDF]  

Yoko Ushijima, Tetsuo Koshizuka, Fumi Goshima, Hiroshi Kimura, and Yukihiro Nishiyama

Herpes Simplex Virus Type 2 UL56 Interacts with the Ubiquitin Ligase Nedd4 and Increases Its Ubiquitination
J. Virol. 2008 82: 5220-5233. [Abstract] [Full Text] [PDF]  

Qinyan Yin, Jane McBride, Claire Fewell, Michelle Lacey, Xia Wang, Zhen Lin, Jennifer Cameron, and Erik K. Flemington

MicroRNA-155 Is an Epstein-Barr Virus-Induced Gene That Modulates Epstein-Barr Virus-Regulated Gene Expression Pathways
J. Virol. 2008 82: 5295-5306. [Abstract] [Full Text] [PDF]  

Liliana Maruri-Avidal, Susana López, and Carlos F. Arias

Endoplasmic Reticulum Chaperones Are Involved in the Morphogenesis of Rotavirus Infectious Particles
J. Virol. 2008 82: 5368-5380. [Abstract] [Full Text] [PDF]  

Liang Shang, Ling Yue, and Eric Hunter

Role of the Membrane-Spanning Domain of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein in Cell-Cell Fusion and Virus Infection
J. Virol. 2008 82: 5417-5428. [Abstract] [Full Text] [PDF]  

John West and Blossom Damania

Upregulation of the TLR3 Pathway by Kaposi's Sarcoma-Associated Herpesvirus during Primary Infection
J. Virol. 2008 82: 5440-5449. [Abstract] [Full Text] [PDF]  

Brian M. Taylor, J. Scott Foulke, Robin Flinko, Alonso Heredia, Anthony DeVico, and Marvin Reitz

An Alteration of Human Immunodeficiency Virus gp41 Leads to Reduced CCR5 Dependence and CD4 Independence
J. Virol. 2008 82: 5460-5471. [Abstract] [Full Text] [PDF]  

Che-Pei Kung and Nancy Raab-Traub

Epstein-Barr Virus Latent Membrane Protein 1 Induces Expression of the Epidermal Growth Factor Receptor through Effects on Bcl-3 and STAT3
J. Virol. 2008 82: 5486-5493. [Abstract] [Full Text] [PDF]  

Tracy Jo Pasieka, Betty Lu, Seth D. Crosby, Kristine M. Wylie, Lynda A. Morrison, Diane E. Alexander, Vineet D. Menachery, and David A. Leib

Herpes Simplex Virus Virion Host Shutoff Attenuates Establishment of the Antiviral State
J. Virol. 2008 82: 5527-5535. [Abstract] [Full Text] [PDF]  

Wei Huang, Jonathan Toma, Signe Fransen, Eric Stawiski, Jacqueline D. Reeves, Jeannette M. Whitcomb, Neil Parkin, and Christos J. Petropoulos

Coreceptor Tropism Can Be Influenced by Amino Acid Substitutions in the gp41 Transmembrane Subunit of Human Immunodeficiency Virus Type 1 Envelope Protein
J. Virol. 2008 82: 5584-5593. [Abstract] [Full Text] [PDF]  

Genome Replication and Regulation of Viral Gene Expression:

Ingo Ammermann, Markus Bruckner, Frank Matthes, Thomas Iftner, and Frank Stubenrauch

Inhibition of Transcription and DNA Replication by the Papillomavirus E8^E2C Protein Is Mediated by Interaction with Corepressor Molecules
J. Virol. 2008 82: 5127-5136. [Abstract] [Full Text] [PDF]  

F. Abaitua and P. O'Hare

Identification of a Highly Conserved, Functional Nuclear Localization Signal within the N-Terminal Region of Herpes Simplex Virus Type 1 VP1-2 Tegument Protein
J. Virol. 2008 82: 5234-5244. [Abstract] [Full Text] [PDF]  

Feng Yang, Jason M. Robotham, Heather B. Nelson, Andre Irsigler, Rachael Kenworthy, and Hengli Tang

Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro
J. Virol. 2008 82: 5269-5278. [Abstract] [Full Text] [PDF]  

Xiaorong Zhao, Ramiro J. Madden-Fuentes, Becky X. Lou, James M. Pipas, Jeannine Gerhardt, Christopher J. Rigell, and Ellen Fanning

Ataxia Telangiectasia-Mutated Damage-Signaling Kinase- and Proteasome-Dependent Destruction of Mre11-Rad50-Nbs1 Subunits in Simian Virus 40-Infected Primate Cells
J. Virol. 2008 82: 5316-5328. [Abstract] [Full Text] [PDF]  

Nang L. Nguyen, Amy N. Loveland, and Wade Gibson

Nuclear Localization Sequences in Cytomegalovirus Capsid Assembly Proteins (UL80 Proteins) Are Required for Virus Production: Inactivating NLS1, NLS2, or Both Affects Replication to Strikingly Different Extents
J. Virol. 2008 82: 5381-5389. [Abstract] [Full Text] [PDF]  

Ivona Pandrea, Richard Onanga, Sandrine Souquiere, Augustin Mouinga-Ondéme, Olivier Bourry, Maria Makuwa, Pierre Rouquet, Guido Silvestri, François Simon, Pierre Roques, and Cristian Apetrei

Paucity of CD4⁺ CCR5⁺ T Cells May Prevent Transmission of Simian Immunodeficiency Virus in Natural Nonhuman Primate Hosts by Breast-Feeding
J. Virol. 2008 82: 5501-5509. [Abstract] [Full Text] [PDF]  

Yi Li and Linda A. Guarino

Roles of LEF-4 and PTP/BVP RNA Triphosphatases in Processing of Baculovirus Late mRNAs
J. Virol. 2008 82: 5573-5583. [Abstract] [Full Text] [PDF]  

Sarah Gallois-Montbrun, Rebecca K. Holmes, Chad M. Swanson, Mireia Fernández-Ocaña, Helen L. Byers, Malcolm A. Ward, and Michael H. Malim

Comparison of Cellular Ribonucleoprotein Complexes Associated with the APOBEC3F and APOBEC3G Antiviral Proteins
J. Virol. 2008 82: 5636-5642. [Abstract] [Full Text] [PDF]  

Pathogenesis and Immunity:

Ousmane M. Diop, Mickaël J.-Y. Ploquin, Lorenzo Mortara, Abdourahmane Faye, Béatrice Jacquelin, Désirée Kunkel, Pierre Lebon, Cécile Butor, Anne Hosmalin, Françoise Barré-Sinoussi, and Michaela C. Müller-Trutwin

Plasmacytoid Dendritic Cell Dynamics and Alpha Interferon Production during Simian Immunodeficiency Virus Infection with a Nonpathogenic Outcome
J. Virol. 2008 82: 5145-5152. [Abstract] [Full Text] [PDF]  

J. H. C. M. Kreijtz, G. de Mutsert, C. A. van Baalen, R. A. M. Fouchier, A. D. M. E. Osterhaus, and G. F. Rimmelzwaan

Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus
J. Virol. 2008 82: 5161-5166. [Abstract] [Full Text] [PDF]  

Nicholas J. Maness, Levi J. Yant, Chungwon Chung, John T. Loffredo, Thomas C. Friedrich, Shari M. Piaskowski, Jessica Furlott, Gemma E. May, Taeko Soma, Enrique J. León, Nancy A. Wilson, Helen Piontkivska, Austin L. Hughes, John Sidney, Alessandro Sette, and David I. Watkins

Comprehensive Immunological Evaluation Reveals Surprisingly Few Differences between Elite Controller and Progressor Mamu-B*17-Positive Simian Immunodeficiency Virus-Infected Rhesus Macaques
J. Virol. 2008 82: 5245-5254. [Abstract] [Full Text] [PDF]  

Olga A. Maximova, Jerrold M. Ward, David M. Asher, Marisa St. Claire, Brad W. Finneyfrock, James M. Speicher, Brian R. Murphy, and Alexander G. Pletnev

Comparative Neuropathogenesis and Neurovirulence of Attenuated Flaviviruses in Nonhuman Primates
J. Virol. 2008 82: 5255-5268. [Abstract] [Full Text] [PDF]  

I. Frank, H. Stössel, A. Gettie, S. G. Turville, J. W. Bess, Jr., J. D. Lifson, I. Sivin, N. Romani, and M. Robbiani

A Fusion Inhibitor Prevents Spread of Immunodeficiency Viruses, but Not Activation of Virus-Specific T Cells, by Dendritic Cells
J. Virol. 2008 82: 5329-5339. [Abstract] [Full Text] [PDF]  

Amy L. Hartman, Ling Ling, Stuart T. Nichol, and Martin L. Hibberd

Whole-Genome Expression Profiling Reveals That Inhibition of Host Innate Immune Response Pathways by Ebola Virus Can Be Reversed by a Single Amino Acid Change in the VP35 Protein
J. Virol. 2008 82: 5348-5358. [Abstract] [Full Text] [PDF]  

Patricia Devaux, Gregory Hodge, Michael B. McChesney, and Roberto Cattaneo

Attenuation of V- or C-Defective Measles Viruses: Infection Control by the Inflammatory and Interferon Responses of Rhesus Monkeys
J. Virol. 2008 82: 5359-5367. [Abstract] [Full Text] [PDF]  

Brinda Emu, Elizabeth Sinclair, Hiroyu Hatano, April Ferre, Barbara Shacklett, Jeffrey N. Martin, J. M. McCune, and Steven G. Deeks

HLA Class I-Restricted T-Cell Responses May Contribute to the Control of Human Immunodeficiency Virus Infection, but Such Responses Are Not Always Necessary for Long-Term Virus Control
J. Virol. 2008 82: 5398-5407. [Abstract] [Full Text] [PDF]  

Tibor Farkas, Karol Sestak, Chao Wei, and Xi Jiang

Characterization of a Rhesus Monkey Calicivirus Representing a New Genus of Caliciviridae
J. Virol. 2008 82: 5408-5416. [Abstract] [Full Text] [PDF]  

Ivan Stratov, Amy Chung, and Stephen J. Kent

Robust NK Cell-Mediated Human Immunodeficiency Virus (HIV)-Specific Antibody-Dependent Responses in HIV-Infected Subjects
J. Virol. 2008 82: 5450-5459. [Abstract] [Full Text] [PDF]  

Jayasri Das Sarma, Kathryn Iacono, Lilli Gard, Ryan Marek, Lawrence C. Kenyon, Michael Koval, and Susan R. Weiss

Demyelinating and Nondemyelinating Strains of Mouse Hepatitis Virus Differ in Their Neural Cell Tropism
J. Virol. 2008 82: 5519-5526. [Abstract] [Full Text] [PDF]  

Brandon F. Keele, Loubna Tazi, Suzanne Gartner, Yiling Liu, Trever B. Burgon, Jacob D. Estes, Tyler C. Thacker, Keith A. Crandall, Justin C. McArthur, and Gregory F. Burton

Characterization of the Follicular Dendritic Cell Reservoir of Human Immunodeficiency Virus Type 1
J. Virol. 2008 82: 5548-5561. [Abstract] [Full Text] [PDF]  

Jinglin Sun, Jian Hua Zheng, Mengliang Zhao, Sunhee Lee, and Harris Goldstein

Increased In Vivo Activation of Microglia and Astrocytes in the Brains of Mice Transgenic for an Infectious R5 Human Immunodeficiency Virus Type 1 Provirus and for CD4-Specific Expression of Human Cyclin T1 in Response to Stimulation by Lipopolysaccharides
J. Virol. 2008 82: 5562-5572. [Abstract] [Full Text] [PDF]  

Arne Schneidewind, Mark A. Brockman, John Sidney, Yaoyu E. Wang, Huabiao Chen, Todd J. Suscovich, Bin Li, Rahma I. Adam, Rachel L. Allgaier, Bianca R. Mothé, Thomas Kuntzen, Cesar Oniangue-Ndza, Alicja Trocha, Xu G. Yu, Christian Brander, Alessandro Sette, Bruce D. Walker, and Todd M. Allen

Structural and Functional Constraints Limit Options for Cytotoxic T-Lymphocyte Escape in the Immunodominant HLA-B27-Restricted Epitope in Human Immunodeficiency Virus Type 1 Capsid
J. Virol. 2008 82: 5594-5605. [Abstract] [Full Text] [PDF]  

Jinjong Myoung, Young Yil Bahk, Hyun Seok Kang, Mauro C. Dal Canto, and Byung S. Kim

Anticapsid Immunity Level, Not Viral Persistence Level, Correlates with the Progression of Theiler's Virus-Induced Demyelinating Disease in Viral P1-Transgenic Mice
J. Virol. 2008 82: 5606-5617. [Abstract] [Full Text] [PDF]  

Ronald S. Veazey, Paula M. Acierno, Kimberly J. McEvers, Susanne H. C. Baumeister, Gabriel J. Foster, Melisa D. Rett, Michael H. Newberg, Marcelo J. Kuroda, Kenneth Williams, Eun-Young Kim, Steven M. Wolinsky, E. Peter Rieber, Michael Piatak, Jr., Jeffrey D. Lifson, David C. Montefiori, Charles R. Brown, Vanessa M. Hirsch, and Jörn E. Schmitz

Increased Loss of CCR5⁺ CD45RA^– CD4⁺ T Cells in CD8⁺ Lymphocyte-Depleted Simian Immunodeficiency Virus-Infected Rhesus Monkeys
J. Virol. 2008 82: 5618-5630. [Abstract] [Full Text] [PDF]  

Eun-Young Kim, Ronald S. Veazey, Roland Zahn, Kimberly J. McEvers, Susanne H. C. Baumeister, Gabriel J. Foster, Melisa D. Rett, Michael H. Newberg, Marcelo J. Kuroda, E. Peter Rieber, Michael Piatak, Jr., Jeffrey D. Lifson, Norman L. Letvin, Steven M. Wolinsky, and Jörn E. Schmitz

Contribution of CD8⁺ T Cells to Containment of Viral Replication and Emergence of Mutations in Mamu-A*01-Restricted Epitopes in Simian Immunodeficiency Virus-Infected Rhesus Monkeys
J. Virol. 2008 82: 5631-5635. [Abstract] [Full Text] [PDF]  

Anice C. Lowen, John Steel, Samira Mubareka, and Peter Palese

High Temperature (30°C) Blocks Aerosol but Not Contact Transmission of Influenza Virus
J. Virol. 2008 82: 5650-5652. [Abstract] [Full Text] [PDF]  

Siu-hong Ho, Nataliya Trunova, Agegnehu Gettie, James Blanchard, and Cecilia Cheng-Mayer

Different Mutational Pathways to CXCR4 Coreceptor Switch of CCR5-Using Simian-Human Immunodeficiency Virus
J. Virol. 2008 82: 5653-5656. [Abstract] [Full Text] [PDF]  

Structure and Assembly:

Nina DiPrimio, Aravind Asokan, Lakshmanan Govindasamy, Mavis Agbandje-McKenna, and R. Jude Samulski

Surface Loop Dynamics in Adeno-Associated Virus Capsid Assembly
J. Virol. 2008 82: 5178-5189. [Abstract] [Full Text] [PDF]  

Christopher B. Buck, Naiqian Cheng, Cynthia D. Thompson, Douglas R. Lowy, Alasdair C. Steven, John T. Schiller, and Benes L. Trus

Arrangement of L2 within the Papillomavirus Capsid
J. Virol. 2008 82: 5190-5197. [Abstract] [Full Text] [PDF]  

Ken Sugimoto, Masashi Uema, Hiroshi Sagara, Michiko Tanaka, Tetsutaro Sata, Yasuhiro Hashimoto, and Yasushi Kawaguchi

Simultaneous Tracking of Capsid, Tegument, and Envelope Protein Localization in Living Cells Infected with Triply Fluorescent Herpes Simplex Virus 1
J. Virol. 2008 82: 5198-5211. [Abstract] [Full Text] [PDF]  

Benjamin W. Neuman, Jeremiah S. Joseph, Kumar S. Saikatendu, Pedro Serrano, Amarnath Chatterjee, Margaret A. Johnson, Lujian Liao, Joseph P. Klaus, John R. Yates, III, Kurt Wüthrich, Raymond C. Stevens, Michael J. Buchmeier, and Peter Kuhn

Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3
J. Virol. 2008 82: 5279-5294. [Abstract] [Full Text] [PDF]  

Weiming Bu, Aygun Mamedova, Ming Tan, Ming Xia, Xi Jiang, and Rashmi S. Hegde

Structural Basis for the Receptor Binding Specificity of Norwalk Virus
J. Virol. 2008 82: 5340-5347. [Abstract] [Full Text] [PDF]  

Inga Dry, David M. Haig, Neil F. Inglis, Lisa Imrie, James P. Stewart, and George C. Russell

Proteomic Analysis of Pathogenic and Attenuated Alcelaphine Herpesvirus 1
J. Virol. 2008 82: 5390-5397. [Abstract] [Full Text] [PDF]  

B. Dancho Swinteck and Douglas S. Lyles

Plasma Membrane Microdomains Containing Vesicular Stomatitis Virus M Protein Are Separate from Microdomains Containing G Protein and Nucleocapsids
J. Virol. 2008 82: 5536-5547. [Abstract] [Full Text] [PDF]  

Transformation and Oncogenesis:

Chae-ryun Yi and Naomi Rosenberg

Mutations Affecting the MA Portion of the v-Abl Protein Reveal a Conserved Role of Gag in Abelson Murine Leukemia Virus (MLV) and Moloney MLV
J. Virol. 2008 82: 5307-5315. [Abstract] [Full Text] [PDF]  

Cellular Response to Infection:

Melvyn W. Yap, Dirk Lindemann, Nicole Stanke, Juliane Reh, Dana Westphal, Helmut Hanenberg, Sadayuki Ohkura, and Jonathan P. Stoye

Restriction of Foamy Viruses by Primate Trim5
J. Virol. 2008 82: 5429-5439. [Abstract] [Full Text] [PDF]  

Vaccines and Antiviral Agents:

Nadja Thönes, Anna Herreiner, Lysann Schädlich, Konrad Piuko, and Martin Müller

A Direct Comparison of Human Papillomavirus Type 16 L1 Particles Reveals a Lower Immunogenicity of Capsomeres than Viruslike Particles with Respect to the Induced Antibody Response
J. Virol. 2008 82: 5472-5485. [Abstract] [Full Text] [PDF]  

Susan J. Little, Simon D. W. Frost, Joseph K. Wong, Davey M. Smith, Sergei L. Kosakovsky Pond, Caroline C. Ignacio, Neil T. Parkin, Christos J. Petropoulos, and Douglas D. Richman

Persistence of Transmitted Drug Resistance among Subjects with Primary Human Immunodeficiency Virus Infection
J. Virol. 2008 82: 5510-5518. [Abstract] [Full Text] [PDF]  

Jinyan Liu, Rune Kjeken, Iacob Mathiesen, and Dan H. Barouch

Recruitment of Antigen-Presenting Cells to the Site of Inoculation and Augmentation of Human Immunodeficiency Virus Type 1 DNA Vaccine Immunogenicity by In Vivo Electroporation
J. Virol. 2008 82: 5643-5649. [Abstract] [Full Text] [PDF]  

Thomas W. Geisbert, Kathleen M. Daddario-DiCaprio, Kinola J. N. Williams, Joan B. Geisbert, Anders Leung, Friederike Feldmann, Lisa E. Hensley, Heinz Feldmann, and Steven M. Jones

Recombinant Vesicular Stomatitis Virus Vector Mediates Postexposure Protection against Sudan Ebola Hemorrhagic Fever in Nonhuman Primates
J. Virol. 2008 82: 5664-5668. [Abstract] [Full Text] [PDF]  

Genetic Diversity and Evolution:

Richard G. Jarman, Edward C. Holmes, Prinyada Rodpradit, Chonticha Klungthong, Robert V. Gibbons, Ananda Nisalak, Alan L. Rothman, Daniel H. Libraty, Francis A. Ennis, Mammen P. Mammen, Jr., and Timothy P. Endy

Microevolution of Dengue Viruses Circulating among Primary School Children in Kamphaeng Phet, Thailand
J. Virol. 2008 82: 5494-5500. [Abstract] [Full Text] [PDF]  

Tran Thien Tuan Huy, Trinh Thi Ngoc, and Kenji Abe

New Complex Recombinant Genotype of Hepatitis B Virus Identified in Vietnam
J. Virol. 2008 82: 5657-5663. [Abstract] [Full Text] [PDF]  

Errata:

Julia Magden, Naokazu Takeda, Tiancheng Li, Petri Auvinen, Tero Ahola, Tatsuo Miyamura, Andres Merits, and Leevi Kääriäinen

Virus-Specific mRNA Capping Enzyme Encoded by Hepatitis E Virus
J. Virol. 2008 82: 5669. [Full Text] [PDF]  

Author's Correction:

B. Feierbach, M. Bisher, J. Goodhouse, and L. W. Enquist

In Vitro Analysis of Transneuronal Spread of an Alphaherpesvirus Infection in Peripheral Nervous System Neurons
J. Virol. 2008 82: 5670. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.