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FIG. 2. Scanning and direct transfer models by which the TMEV IRES can use alternate start codons. The IRES and a conserved oligopyrimidine-rich sequence motif (Yn) are shown in green. The ribosomal 48S complex is depicted. 40S subunits are light blue; 40S-associated eIF-2 and eIF-3 are red and blue, respectively; initiator tRNA is black. The ITAF is shown in yellow. The start-site AUG codons for the viral polyprotein and various L* proteins are shown. See the text for details.
